English: Inflammasome, a multiprotein complex that mediates the activation of Caspase-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
Image modified based on Tessa Bergsbaken pyroptosis: host cell death and inflammation doi:10.1038/nrmicro2070 M.Dagenais and A.Skeldon and M.Saleh The inflammasome: in memory of Dr. Jurg Tschopp Cell Death and Differentiation (2012) 19, 5–12; doi:10....